Synthesis, crystal structure and spectral properties of 6-bromo-N-(cyclohex-1-en-1-ylmethyl)-4-oxo-4H-chromene-2-carboxamide

• Type: Article in International Scientific Journal
• Date: 2013

Authors

cagide, fernando (Author) FCUP; borges, fernanda (Author) FCUP; gomes, ligia rebelo (Author) Other; low, john nicolson (Author) Other

Journal

Title: Journal of Molecular Structure

Vol. 1049

Pages: 125-131

ISSN: 0022-2860

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 1 Citation

Other information

Authenticus ID: P-006-6MG

DOI: 10.1016/j.molstruc.2013.06.028

Abstract (EN): In this work the synthesis of a new chromone (6-bromo-N-(cyclohex-1-en-1-ylmethyl)-4-oxo-4H-chromene-2-carboxamide) by a strategy performed in three steps is reported. The compound was characterized by NMR (H-1 and C-13) and EIMS and the structure was confirmed by single-crystal X-ray diffraction. The analysis of the X-ray determined that the molecule is built up from two rings, a chromone ring and a cyclohexene ring united by an amide spacer. This new chromone will be valuable for obtaining evidence about the importance of the exocyclic double bound on monoaminoxidase-B (MAO-B) inhibitory activity. (c) 2013 Published by Elsevier B.V.

Language: English

Type (Professor's evaluation): Scientific