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Oxidative behaviour of apomorphine and its metabolites

Title
Oxidative behaviour of apomorphine and its metabolites
Type
Article in International Scientific Journal
Year
2002
Authors
Garrido, JMPJ
(Author)
Other
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Delerue Matos, C
(Author)
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Borges, MFM
(Author)
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Macedo, TRA
(Author)
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Oliveira Brett, AM
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Journal
Title: BioelectrochemistryImported from Authenticus Search for Journal Publications
Vol. 55
ISSN: 1567-5394
Publisher: Elsevier
Scientific classification
FOS: Natural sciences > Chemical sciences
Other information
Authenticus ID: P-000-QWQ
Abstract (EN): The metabolism of apomorphine is quite complex due to interactions with proteins and other tissue components that affect its pharmacokinetic profile. The electrochemical oxidation mechanism of apomorphine and of some synthesised apomorphine derivatives was studied. It was found to be related to the reaction of o-diphenol and tertiary amine groups and strongly dependent on pH. (C) 2002 Elsevier Science B.V. All rights reserved.
Language: English
Type (Professor's evaluation): Scientific
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