3D echocardiography facing the challenge of diastolic function evaluation

• Type: Summary of Presentation in an International Conference
• Date: 2012

Authors

Gonçalves A (Author) Other; Sousa C (Author) Other; Rangel I (Author) Other; Correia AS (Author) Other; Macedo F (Author) Other; Zamorano JL (Author) Other; Maciel MJ (Author) FMUP

Conference proceedings International

Title: European Heart Journal

Pages: 726-726

ESC Congress 2012

Munich, 25 a 29 de Agosto de 2012

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Abstract (EN): Introduction: Left atrial (LA) ejection fraction has been recently recognized as a marker of diastolic dysfunction. LAVi/A' ratio was shown to be an indicator of advanced diastolic dysfunction and predictor of paroxysmal atrial fibrillation. In this study we aimed to assess the relation of LA ejection fraction by 3D echocardiography with new parameters of diastolic evaluation. Methods: 40 patients, among which 29 patients with hypertrophic cardiomyopathy with parameters of elevated left ventricle filling pressure (E/E'≥10) and 11 controls with normal left ventricle filling pressure were prospective enrolled for 3D transthoracic echocardiography by one heart beat (ACUSON SC2000 TM, Siemens Medical Solutions USA Inc.). Left ventricle systolic function and left atrium ejection fraction were assessed by 3D volumes automatic calculation. Pulsed Doppler through mitral valve and tissue Doppler parameters was measured according to the recommended guidelines. Results: Patients with elevated left ventricle filling pressures presented higher LA maximum (71.2±31.4 ml vs 50.5±19.5 ml; p=0.045) and minimum volumes (44.4±26.4 ml vs 22.3±10.3 ml; p=0.039) and lower LA ejection fraction (39.9±14.9 ml vs 55.7±13.0 ml; p=0.015) in spite of similar left ventricle diastolic (127.8±54.0 ml vs 115.0±41.3 ml) and systolic (39.9±14.9 ml vs 55.7±13.0 ml) volumes and left ventricle ejection fraction (55.7±12.5% vs 58.2±5.4%). LAVi/A' ratio was significantly higher in patients with elevated left ventricle filling pressures (7.1±5.2 vs 3.7±2.5; p= 0.03) and LA ejection fraction presented a significant negative correlation with LAVi/A' ratio (r=-0.43, p=0.042). Area under the receiver operating characteristic curve to diagnose elevated left ventricle filling pressures by LA ejection fraction was 0.814 (0.653; 0.975). Conclusion: LA ejection fraction by 3D echocardiography recognizes patients with elevated left ventricle filling pressures, therefore it might be valuable alternative at time of diastolic function evaluation.

Language: English

Type (Professor's evaluation): Scientific

Notes: Gonçalves A, Sousa C, Rangel I, Correia AS, Macedo F, Zamorano JL, Maciel MJ. 3D echocardiography facing the challenge of diastolic function evaluation. Eur Heart J 2012; 33 (Abstract Suppl): 726