The metabolic syndrome

• Type: Chapter or Part of a Book
• Date: 2009

Authors

Azevedo A (Author) FMUP; Santos AC (Author) FMUP; Ribeiro L (Author) FMUP; Azevedo I (Author) FMUP

Book

Title: Oxidative stress, inflammation and angiogenesis in the metabolic syndrome

Pages: 1-19

ISBN: 978-1-4020-9700-3

Publisher: Springer

Indexing

Scopus - 12 Citations

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

Other information

Authenticus ID: P-009-5RV

DOI: 10.1007/978-1-4020-9701-0_1

Abstract (EN): Cardiovascular risk factors have a tendency to co-aggregate. One of the most well studied of these co-aggregations is the overlap between insulin resistance, obesity, hypertension and dyslipidaemia, now labelled as metabolic syndrome. Although metabolic syndrome is multifactorial, there is a growing belief that visceral obesity may play an important role in the development of the syndrome. More recently, adipocyte hypertrophy is also getting much attention. Susceptibility to the metabolic syndrome encompasses genetic factors and environmental conditions during early life, including intra-uterine time. Environmental factors, namely related with lifestyles - oscillation between work and rest, sleeping time, quality and quantity of food and meal schedule, social organization, level of stress and physical activity, play a paramount role in its causation and progressive development of superimposing vicious cycles. The consequences of the syndrome are many, with relevance to cardiovascular disease and diabetes. The proportion of affected people in the present world, together with the diverse nature of associating/causative factors, warrants a highly committed multidisciplinary effort from the whole society to deal with the problem. © 2009 Springer Netherlands.

Language: English

Type (Professor's evaluation): Scientific