Incidence of Myocardial Injury in Patients Submitted to Abdominal Aortic Aneurysm Repair: A Systematic Review and Meta-Analysis

• Type: Another Publication in an International Scientific Journal
• Date: 2025

Authors

Francisco Azevedo, J (Author) Other; Romana Dias, L (Author) Other; Ribeiro, H (Author) Other; Dias Neto, M (Author) Other; Rocha Neves, J (Author) FMUP

Journal

Title: Annals of Vascular Surgery

Vol. 120

Pages: 57-76

ISSN: 0890-5096

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-018-REQ

DOI: 10.1016/j.avsg.2025.05.006

Abstract (EN): Background: Repair of abdominal aortic aneurysms (AAAs) is a major vascular surgery that carries risk of myocardial injury following noncardiac surgery (MINS). MINS occurs in approximately 20% of patients and affects patient outcomes, but its incidence remains unclear in this subset of patients. This systematic review aims to determine the incidence of MINS in patients undergoing AAA repair. Methods: MEDLINE, Web of Science, and Scopus were searched for studies assessing MINS after AAA repair. The incidence of MINS in endovascular aortic repair (EVAR) and open aortic repair (OAR) was pooled by random-effects meta-analysis, with sources of heterogeneity being explored. Assessment of studies' quality was performed using National Heart, Lung, and Blood Institute Study Quality Assessment and RoB 2 Tool. Results: Sixteen studies were included, with a total of 25,649 participants. Two were randomized controlled trials, while the remaining were cohorts. Age ranged from 65.8-75.5 and percentage of male participants between 78% and 96.6%. The pooled incidence of MINS ranged from 0.4% to 18.7% for EVAR and 1.8-46.8% for OAR. Meta-analytical incidence of MINS after EVAR was 12.5% (95% confidence interval [CI] 6.2-18.7%) in cohort studies and 0.9% (95% CI 0.4-1.4%) in multicenter database studies, both with severe heterogeneity (I2-91.0% and 79.1%). For OAR, the incidence was 30.6% (95% CI 19.5-41.7%) in cohort studies, 3.2% (95% CI 1.8-4.6%) in multicenter database studies, and 32.4% (95% CI 18.1-46.8%) in randomized controlled trials, all with high heterogeneity (I2-96.8%, 86.6%, and 71.3%).

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 20