Maternal Early-onset Preeclampsia Places Preterm Infants at Risk of Thrombocytopenia Requiring Platelet Transfusions

• Type: Article in International Scientific Journal
• Date: 2025

Authors

Pereira, J (Author) Other; Rabiço Costa, D (Author) Other; Marques, M (Author) Other; Moita, R (Author) Other; Ferreras, C (Author) Other; Flôr De Lima, F (Author) Other; Inês Azevedo (Author) FMUP; Rocha, G (Author) Other

Journal

Title: Journal of Pediatric Hematology/Oncology

Vol. 47

Pages: 177-184

ISSN: 1077-4114

Publisher: Wolters Kluwer Health

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-018-K6Y

DOI: 10.1097/mph.0000000000003022

Abstract (EN): Objectives: Evaluate the hematological parameters and indices in the blood count collected on the first day of life (D1) in very premature infants born to mothers with early-onset preeclampsia (PE) and their correlation with increased neonatal morbimortality. Background: Changes in hematologic parameters in the blood counts collected after birth associated with PE have been demonstrated by recent studies, although inconsistently. Materials and Methods: Retrospective study between 2008 and 2023, at a level III neonatal intensive care unit, including preterm infants with a gestational age below 30 weeks. A blood count was collected on D1 and a comparison of hematological parameters and indices was made between infants exposed or not to PE. Results: We included 206 newborns (PE = 39; no PE = 167). The multivariate analyses showed no significant hematological changes. PE-exposed infants required significantly more platelet transfusions (PE: n = 20 [51.8%]; no PE: n = 34 [20.36%]; P < 0.0001). Conclusion: PE-exposed preterms required more platelet transfusions, which increases the risk of associated complications. Copyright © 2025 Wolters Kluwer Health, Inc.

Language: English

Type (Professor's evaluation): Scientific