Pieris brassicae Inhibits Xanthine Oxidase

• Type: Article in International Scientific Journal
• Date: 2009

Authors

Carla Sousa (Author) FFUP; David M Pereira (Author) Other; Patricia Valentao (Author) FFUP; Federico Ferreres (Author) Other; Jose A Pereira (Author) Other; Rosa M Seabra (Author) Other; Paula B Andrade (Author) FFUP

Journal

Title: Journal of Agricultural and Food Chemistry

Vol. 57 No. 19

Pages: 2288-2294

ISSN: 0021-8561

Publisher: American Chemical Society

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 11 Citations

Scientific classification

FOS: Agrarian Sciences > Other Agrarian Sciences

Other information

Authenticus ID: P-003-MET

DOI: 10.1021/jf803831v

Resumo (PT): The antioxidant potential of an aqueous extract obtained from Pieris brassicae larvae reared on Brassica oleracea L. var. costata DC was evaluated against 2,2-diphenyl-1-picrylhydrazyl radical and several reactive oxygen species. The results revealed an effective concentration-dependent protective activity against superoxide and hydroxyl radicals, being superior to that of the host plant. In addition, the larvae extract also exhibited a strong inhibitory effect on xanthine oxidase that was not observed for B. oleracea var. costata. A weak scavenging ability was noticed for hypochlorous acid. Several phenolic compounds with complex chemical structures that are hard to synthesize in the laboratory were found in P. brassicae extract. This is the first time that an insect has been tested for its xanthine oxidase inhibitory capacity, which proved to be very high. These findings are interesting considering that they can be used by food or pharmaceutical industries to prevent the oxidation of their products, to increase the dietary supply of antioxidants, or for prevention of free radical-mediated diseases, namely, gout. <br> <br> <a target="_blank" href="http://pubs.acs.org/doi/abs/10.1021/jf803831v"> Texto integral</a> <br> <br>

Abstract (EN): The antioxidant potential of an aqueous extract obtained from Piefis brassicae larvae reared on Brassica oleracea L. var. costata DC was evaluated against 2,2-diphenyl-1-picrylhydrazyl radical and several reactive oxygen species. The results revealed an effective concentration-dependent protective activity against superoxide and hydroxyl radicals, being superior to that of the host plant. In addition, the larvae extract also exhibited a strong inhibitory effect on xanthine oxidase that was not observed for B. oleracea var. costata. A weak scavenging ability was noticed for hypochlorous acid. Several phenolic compounds with complex chemical structures that are hard to synthesize in the laboratory were found in P. brassicae extract. This is the first time that an insect has been tested for its xanthine oxidase inhibitory capacity, which proved to be very high. These findings are interesting considering that they can be used by food or pharmaceutical industries to prevent the oxidation of their products, to increase the dietary supply of antioxidants, or for prevention of free radical-mediated diseases, namely, gout.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7