Endoscopic Ultrasound-Guided Through-the-Needle Biopsy: A Narrative Review of the Technique and Its Emerging Role in Pancreatic Cyst Diagnosis

• Type: Another Publication in an International Scientific Journal
• Date: 2024

Authors

Vilas-Boas, F (Author) Other; Ribeiro, T (Author) Other; Macedo G (Author) FMUP; Dhar, J (Author) Other; Samanta, J (Author) Other; Sina, S (Author) Other; Manfrin, E (Author) Other; Facciorusso, A (Author) Other; Conti Bellocchi, MC (Author) Other; De Pretis, N (Author) Other; Frulloni, L (Author) Other; Crinò, SF (Author) Other

Journal

Title: Diagnostics

Publisher: MDPI

Other information

Authenticus ID: P-015-96Q

DOI: 10.3390/diagnostics14151587

Abstract (EN): <jats:p>Pancreatic cystic lesions (PCLs) pose a diagnostic challenge due to their increasing incidence and the limitations of cross-sectional imaging and endoscopic-ultrasound-guided fine-needle aspiration (EUS-FNA). EUS-guided through the needle biopsy (EUS-TTNB) has emerged as a promising tool for improving the accuracy of cyst type determination and neoplastic risk stratification. EUS-TTNB demonstrates superior diagnostic performance over EUS-FNA, providing critical preoperative information that can significantly influence patient management and reduce unnecessary surgeries. However, the procedure has risks, with an overall adverse event rate of approximately 9%. Preventive measures and further prospective studies are essential to optimize its safety and efficacy. This review highlights the potential of EUS-TTNB to enhance the diagnostic and management approaches for patients with PCLs. It examines the current state of EUS-TTNB, including available devices, indications, procedural techniques, specimen handling, diagnostic yield, clinical impact, and associated adverse events.</jats:p>

Language: English

Type (Professor's evaluation): Scientific