Decoding the Biology of Exosomes in Metastasis

• Type: Another Publication in an International Scientific Journal
• Date: 2020

Authors

Adem, B (Author) Other; Vieira, PF (Author) Other; Melo, SA (Author) FMUP

Journal

The Journal is awaiting validation by the Administrative Services.

Title: TRENDS IN CANCER

Vol. 6

Pages: 20-30

ISSN: 2405-8033

Publisher: CELL PRESS

Indexing

ISI Web of Knowledge - 23 Citations

Scopus - 20 Citations

Other information

Authenticus ID: P-00R-KNF

DOI: 10.1016/j.trecan.2019.11.007

Abstract (EN): Metastasis is the leading cause of cancer mortality. Cancer cells must adapt to colonize and thrive at the metastatic site. The modulation of the receptive organ microenvironment is a key event in the adaptation process and is partially accomplished at a distance by the primary tumor. Exosomes, a subclass of extracellular vesicles (EVs), are distal mediators of communication that carry genetic and molecular information to neighboring and distant cells. Cancer exosomes have been involved in restructuring metastatic sites to support cancer cell colonization. In this article, we discuss the role of exosomes in the metastatic process.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 11