Advances in exosomes utilization for clinical applications in cancer

• Type: Another Publication in an International Scientific Journal
• Date: 2024-08-20

Authors

Batista, IA (Author) Other; Machado JC (Author) FMUP; Sónia Melo (Author) FMUP

Journal

The Journal is awaiting validation by the Administrative Services.

Title: TRENDS IN CANCER

Vol. 10

Pages: 947-968

ISSN: 2405-8033

Publisher: CELL PRESS

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-016-W4M

DOI: 10.1016/j.trecan.2024.07.010

Abstract (EN): Exosomes are regarded as having transformative potential for clinical applications. Exosome-based liquid biopsies offer a noninvasive method for early cancer detection and real-time disease monitoring. Clinical trials are underway to validate the efficacy of exosomal biomarkers for enhancing diagnostic accuracy and predicting treatment responses. Additionally, engineered exosomes are being developed as targeted drug delivery systems that can navigate the bloodstream to deliver therapeutic agents to tumor sites, thus enhancing treatment efficacy while minimizing systemic toxicity. Exosomes also exhibit immunomodulatory properties, which are being harnessed to boost antitumor immune responses. In this review, we detail the latest advances in clinical trials and research studies, underscoring the potential of exosomes to revolutionize cancer care.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 22