Strength of round and uterosacral ligaments: a biomechanical study

• Type: Article in International Scientific Journal
• Date: 2013

Authors

martins, p (Author) FEUP; silva, al (Author) Other; fonseca, amrm (Author) Other; santos, a (Author) Other; santos, l (Author) Other; mascarenhas, t (Author) FMUP; jorge, rmn (Author) FEUP; ferreira, am (Author) Other

Journal

Title: Archives of Gynecology and Obstetrics

Vol. 287

Pages: 313-318

ISSN: 0932-0067

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 27 Citations

ISI Web of Science

Scopus - 29 Citations

Pubmed / Medline

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

CORDIS: Health sciences > Medical sciences > Medicine > Gynaecology

Other information

Authenticus ID: P-002-10M

DOI: 10.1007/s00404-012-2564-3

Abstract (EN): To investigate the tensile biomechanical properties of round and uterosacral ligaments. Tissue samples were obtained from 15 female cadavers without pelvic organ prolapse. Uniaxial tensile tests were performed to obtain stiffness and maximum stress of round and uterosacral ligaments. Correlations were calculated using the Pearson correlation coefficient. Statistical differences between groups were tested using Student's paired and unpaired t test. There was a great variability in the measurements of stiffness and maximum stress in pelvic ligaments. The round ligaments demonstrated stiffness of 9.1 +/- A 1.6 MPa (mean +/- A SEM) (ranging from 2 to 25.6 MPa) and maximum stress of 4.3 +/- A 0.7 MPa (ranging from 1.2 to 11.5 MPa). The stiffness of the uterosacral ligaments was 14.1 +/- A 1.4 MPa (ranging from 5.7 to 26.1 MPa) with maximum stress of 6.3 +/- A 0.8 MPa (ranging from 2.2 to 11.9 MPa). There was a strong positive correlation between stiffness and maximum stress in female pelvic ligaments (rho = 0.851; p < 0.001). The uterosacral ligaments demonstrated higher stiffness and maximum stress compared to the round ligaments (p = 0.006 and p = 0.034; respectively). Age, body mass index and menopausal status were not associated with the biomechanical proprieties of round and uterosacral ligaments. Nulliparous women had lower uterosacral stiffness (15.5 +/- A 1.3 vs. 10 +/- A 1.8 MPa; p = 0.033) and maximum stress (8.2 +/- A 0.9 vs. 4.2 +/- A 1.1 MPa; p = 0.028) compared to parous women. The uterosacral ligaments are significantly more resistant than round ligaments. Parturition seems to enhance the stiffness and maximum stress of the ligaments.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6