Clinical standards for drug-susceptible pulmonary TB

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Akkerman, OW (Author) Other; Duarte R (Author) ICBAS; Tiberi, S (Author) Other; Schaaf, HS (Author) Other; Lange, C (Author) Other; Alffenaar, JWC (Author) Other; Denholm, J (Author) Other; Carvalho, ACC (Author) Other; Bolhuis, MS (Author) Other; Borisov, S (Author) Other; Bruchfeld, J (Author) Other; Cabibbe, AM (Author) Other; Caminero, JA (Author) Other; Carvalho, I (Author) Other; Chakaya, J (Author) Other; Centis, R (Author) Other; Dalcomo, MP (Author) Other; Ambrosio, LD (Author) Other; Dedicoat, M (Author) Other; Dheda, K (Author) Other; Dooley, KE (Author) Other; Furin, J (Author) Other; Garcia Garcia, JM (Author) Other; van Hest, NAH (Author) Other; de Jong, BC (Author) Other; Kurhasani, X (Author) Other; Martson, AG (Author) Other; Mpagama, S (Author) Other; Torrico, MM (Author) Other; Nunes, E (Author) Other; Ong, CWM (Author) Other; Palmero, DJ (Author) Other; Ruslami, R (Author) Other; Saktiawati, AMI (Author) Other; Semuto, C (Author) Other; Silva, DR (Author) Other; Singla, R (Author) Other; Solovic, I (Author) Other; Srivastava, S (Author) Other; de Steenwinkel, JEM (Author) Other; Story, A (Author) Other; Sturkenboom, MGG (Author) Other; Tadolini, M (Author) Other; Udwadia, ZF (Author) Other; Verhage, AR (Author) Other; Zellweger, JP (Author) Other; Migliori, GB (Author) Other

Journal

Title: The International Journal of Tuberculosis and Lung Disease

Vol. 26

Pages: 592-604

ISSN: 1027-3719

Publisher: International Union Against Tuberculosis And Lung Disease

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 0 Citations

Other information

Authenticus ID: P-00W-W12

DOI: 10.5588/ijtld.22.0228

Abstract (EN): BACKGROUND: The aim of these clinical standards is to provide guidance on 'best practice' for diagnosis, treatment and management of drug-susceptible pulmonary TB (PTB). METHODS: A panel of 54 global experts in the field of TB care, public health, microbiology, and pharmacology were identified; 46 participated in a Delphi process. A 5point Likert scale was used to score draft standards. The final document represents the broad consensus and was approved by all 46 participants. RESULTS: Seven clinical standards were defined: Standard 1, all patients (adult or child) who have symptoms and signs compatible with PTB should undergo investigations to reach a diagnosis; Standard 2, adequate bacteriological tests should be conducted to exclude drug-resistant TB; Standard 3, an appropriate regimen recommended by WHO and national guidelines for the treatment of PTB should be identified; Standard 4, health education and counselling should be provided for each patient starting treatment; Standard 5, treatment monitoring should be conducted to assess adherence, follow patient progress, identify and manage adverse events, and detect development of resistance; Standard 6, a recommended series of patient examinations should be performed at the end of treatment; Standard 7, necessary public health actions should be conducted for each patient. We also identified priorities for future research into PTB. CONCLUSION: These consensus-based clinical standards will help to improve patient care by guiding clinicians and programme managers in planning and implementation of locally appropriate measures for optimal person-centred treatment for PTB.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 13