Geographic patterns and hotspots of pediatric tuberculosis: the role of socioeconomic determinants; [Abandono da terapia antirretroviral entre adolescentes e jovens com HIV/aids durante a COVID-19: estudo caso-controle]; [Abandono de la terapia antirretroviral entre adolescentes y jóvenes con VIH/SIDA durante el COVID-19: un estudio de casos y controles]

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Dias, S (Author) Other; Castro, S (Author) Other; Ribeiro, AI (Author) Other; Krainski, T (Author) Other; Duarte R (Author) ICBAS

Journal

Title: Jornal Brasileiro de Pneumologia

Vol. 49

ISSN: 1806-3713

Publisher: Sociedade Brasileira de Pneumologia e Tisiologia

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-00Y-R0Z

DOI: 10.36416/1806-3756/e20230004

Abstract (EN): <jats:p>Objective: Children are an important demographic group for understanding overall tuberculosis epidemiology, and monitoring of childhood tuberculosis is essential for appropriate prevention. The present study sought to characterize the spatial distribution of childhood tuberculosis notification rates in continental Portugal; identify high-risk areas; and evaluate the association between childhood tuberculosis notification rates and socioeconomic deprivation. Methods: Using hierarchical Bayesian spatial models, we analyzed the geographic distribution of pediatric tuberculosis notification rates across 278 municipalities between 2016 and 2020 and determined high-risk and low-risk areas. We used the Portuguese version of the European Deprivation Index to estimate the association between childhood tuberculosis and area-level socioeconomic deprivation. Results: Notification rates ranged from 1.8 to 13.15 per 100,000 children under 5 years of age. We identified seven high-risk areas, the relative risk of which was significantly above the study area average. All seven high-risk areas were located in the metropolitan area of Porto or Lisbon. There was a significant relationship between socioeconomic deprivation and pediatric tuberculosis notification rates (relative risk = 1.16; Bayesian credible interval, 1.05-1.29). Conclusions: Identified high-risk and socioeconomically deprived areas should constitute target areas for tuberculosis control, and these data should be integrated with other risk factors to define more precise criteria for BCG vaccination.</jats:p>

Language: English

Type (Professor's evaluation): Scientific