Protein adsorption effect on in vitro acellular biodegradation of CaO-P2O5 glass ceramics

• Type: Article in International Scientific Journal
• Date: 2004

Authors

Anabela Dias (Author) Other; Maria Ascensão Lopes (Author) FEUP; José Domingos Santos (Author) FEUP

Journal

Title: ADVANCED MATERIALS FORUM II

Vol. 455-456

Pages: 398-401

Publisher: Trans Tech Publications Ltd

Indexing

ISI Web of Knowledge - 2 Citations

ISI Web of Science

Scopus - 2 Citations

Scientific classification

FOS: Engineering and technology > Materials engineering

Other information

Authenticus ID: P-000-C3J

DOI: 10.4028/www.scientific.net/MSF.455-456.398

Abstract (EN): This work reports the in vitro accelular behaviour of a glass ceramic (45P(2)O(5)-45CaO-5MgO-5K(2)O), which has significant potential for being used as an alloplastic bone graft. Experiments were carried out by immersing granule samples for a period up to 90 days in Tris-buffer solution at pH 7.4, in the presence and absence of a foetal bovine serum (FBS). The release of calcium, phosphorus, and potassium ions as well as the amount of protein adsorbed was followed by several techniques. The results obtained seem to indicate that the adsorption of proteins on the surface of the material, although causing an initial delay in the degradation, does not hamper the ionic exchange and therefore it is not a barrier for the degradation of the glass ceramic.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4