Underestimated Prediabetic Biomarkers: Are We Blind to Their Strategy?

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Luís, C (Author) Other; soares, r (Author) FMUP; Baylina, P (Author) Other; Fernandes, R (Author) Other

Journal

Title: Frontiers In Endocrinology

ISSN: 1664-2392

Publisher: Frontiers Media

Indexing

ISI Web of Knowledge - 2 Citations

Scopus - 2 Citations

Other information

Authenticus ID: P-00W-CEX

DOI: 10.3389/fendo.2022.805837

Abstract (EN): Type 2 Diabetes (T2D) is currently one of the fastest growing health challenging, a non-communicable disease result of the XXI century lifestyle. Given its growing incidence and prevalence, it became increasingly imperative to develop new technologies and implement new biomarkers for early diagnosis in order to promote lifestyle changes and thus cause a setback of the disease. Promising biomarkers have been identified as predictive of T2D development; however, none of them have yet been implemented in clinical practice routine. Moreover, many prediabetic biomarkers can also represent potential therapeutical targets in disease management. Previous studies have identified the most popular biomarkers, which are being thoroughly investigated. However, there are some biomarkers with promising preliminary results with limited associated studies; hence there is still much to be understood about its mechanisms and associations in T2D pathophysiology. This work identifies and discusses the promising results of Galectin-3, Ophthalmate and Fetuin-A.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7