Multi-Gene Panel Testing in Gastroenterology: Are We Ready for the Results?

• Type: Another Publication in an International Scientific Journal
• Date: 2021

Authors

Pereira, F (Author) Other; Manuel R Teixeira (Author) ICBAS; Ribeiro, MD (Author) Other; Brandao, C (Author) Other

Journal

Title: GE Portuguese Journal Of Gastroenterology

Vol. 28

Pages: 403-409

ISSN: 2341-4545

Publisher: Karger

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00T-GEV

DOI: 10.1159/000513966

Abstract (EN): Genetic testing aims to identify patients at risk for inherited cancer susceptibility. In the last decade, there was a significant increase in the request of broader panels of genes as multi-gene panel testing became widely available. However, physicians may be faced with genetic findings for which there is lack of management evidence, despite some progress in understanding their clinical relevance. In this short review, we discuss the advantages and the drawbacks related to multi-gene panel testing in the setting of a Gastrointestinal Familial Cancer Risk clinic. We also summarize the available recommendations on management of pathogenic variant carriers.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7