Performance of risk scores in patients with acute exacerbations of COPD

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Gomes, L (Author) Other; Pereira, S (Author) Other; Sousa Pinto, B (Author) FMUP; Rodrigues, C (Author) Other

Journal

Title: Jornal Brasileiro de Pneumologia

Vol. 49

ISSN: 1806-3713

Publisher: Sociedade Brasileira de Pneumologia e Tisiologia

Indexing

ISI Web of Knowledge - 3 Citations

Other information

Authenticus ID: P-00Z-704

DOI: 10.36416/1806-3756/e20230032

Abstract (EN): Objective: Acute exacerbations of COPD (AECOPD) are common causes of hospitalization. Various scoring systems have been proposed to classify the risk of clinical deterioration or mortality in hospitalized patients with AECOPD. We sought to investigate whether clinical deterioration and mortality scores at admission can predict adverse events occurring during hospitalization and after discharge of patients with AECOPD. Methods: We performed a retrospective study of patients admitted with AECOPD. The National Early Warning Score 2 (NEWS2), the NEWS2 88-92%, the Dyspnea, Eosinopenia, Consolidation, Acidemia, and atrial Fibrillation (DECAF) score, and the modified DECAF (mDECAF) score were calculated at admission. We assessed the sensitivity, specificity, and overall performance of the scores for the following outcomes: in-hospital mortality; need for invasive mechanical ventilation or noninvasive ventilation (NIV); long hospital stays; hospital readmissions; and future AECOPD. Results: We included 119 patients admitted with AECOPD. The median age was 75 years, and 87.9% were male. The NEWS2 88-92% was associated with an 8.9% reduction in the number of individuals classified as requiring close, continuous observation, without an increased risk of death in the group of individuals classified as being low-risk patients. The NEWS2 88-92% and NEWS2 scores were found to be adequate in predicting the need for acute NIV and longer hospital stays. The DECAF and mDECAF scores were found to be better at predicting in-hospital mortality than the NEWS2 and NEWS2 88-92%. Conclusions: The NEWS2 88-92% safely reduces the need for clinical monitoring in patients with AECOPD when compared with the NEWS2. The NEWS2 and NEWS2 88-92% appear to be good predictors of the length of hospital stay and need for NIV, but they do not replace the DECAF and mDECAF scores as predictors of mortality.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7