Go to:
Logótipo
Você está em: Start > Publications > View > Gastric Bypass with Different Biliopancreatic Limb Lengths Results in Similar Post-absorptive Metabolomics Profiles
Map of Premises
Principal
Publication

Gastric Bypass with Different Biliopancreatic Limb Lengths Results in Similar Post-absorptive Metabolomics Profiles

Title
Gastric Bypass with Different Biliopancreatic Limb Lengths Results in Similar Post-absorptive Metabolomics Profiles
Type
Article in International Scientific Journal
Year
2019
Authors
Jarak, I
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Pereira, SS
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Carvalho, RA
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Oliveira, PF
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Alves, MG
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Guimarães, M
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Wewer Albrechtsen, NJ
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Holst, JJ
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Nora, M
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Monteiro, M
(Author)
ICBAS
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page Without ORCID
Journal
Title: Obesity SurgeryImported from Authenticus Search for Journal Publications
ISSN: 0960-8923
Publisher: Springer Nature
Indexing
Other information
Authenticus ID: P-00R-FR1
Abstract (EN): Background/Aim: Roux-en-Y gastric bypass (RYGB) with a long biliopancreatic limb (BPL) was demonstrated to further improve type 2 diabetes (T2D) outcomes. Whether benefits occur at the cost of a negative impact on nutrient absorption is a matter of debate. Our aim was to evaluate the impact of RYGB BPL length on short-term nutrient absorption. Methods: Subjects (N = 20) submitted to RYGB with a 2 m BPL (n = 11) or standard BPL (60¿100 cm) (n = 9) 4.2 ± 0.4 years earlier underwent a mixed meal tolerance test. Plasma metabolites were analyzed at baseline and after meal by nuclear magnetic resonance (NMR) spectroscopy. Spectra were subject to multivariate analysis (MVA). Partial least square discriminant analysis (PLS-DA) was used to identify metabolites responsible for group discrimination. Results: Principal component analysis and PLS-DA showed a clear separation between plasma metabolites before and 30 min after meal intake in both groups. The metabolites responsible for differences between time points were glucose and branched-chain amino acids. A complete overlap in metabolite species and concentrations was observed at 0 and 30 min time points for both groups, while acetate levels 120 min after the meal intake were significantly higher in subjects submitted to RYGB with a 2-m-long BPL as compared to the group submitted to the standard RYGB procedure. Conclusions: Post-prandial plasma metabolomics profiles suggest that a 2-m-long BLP RYGB does not have a negative impact on acute metabolite absorption. RYGB BPL length seems to influence post-prandial acetate levels, which could contribute to the additional positive metabolic outcomes. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
Language: English
Type (Professor's evaluation): Scientific
Documents
We could not find any documents associated to the publication.
Related Publications

Of the same journal

Letter to the Editor Concerning Nutritional Deficiencies, Bariatric Surgery, and Serum Homocysteine Level: Review of Current Literature (2020)
Another Publication in an International Scientific Journal
Paredes, S; de Lurdes Fernandes Alves, MDF; ribeiro, l
Central Retinal Vein Occlusion after Gastric Bypass Surgery (2020)
Another Publication in an International Scientific Journal
Laiginhas, R; Esteves Leandro, J; Cardoso, P; Santos Sousa, H; John Preto; Falcão-Reis F; Manuel Falcão
Age and Weight Loss After Bariatric Surgery: Cause or Consequence? (2014)
Another Publication in an International Scientific Journal
Faria, Gil; Pestana, Diogo; John Preto; guimaraes, jt; Gomes AT; Conceicao Calhau
Understanding Obesity Phenotypes: CT Findings Correlate with Metabolic Syndrome (2012)
Other Publications
faria, g; preto, j; da costa, el; almeida, ab; maia, jc; guimaraes, jt; calhau, c; taveira-gomes, a
Pre-operative Glycemic Control is Directly Related with Weight Loss After RYGB (2012)
Other Publications
faria, g; preto, j; da costa, el; almeida, ab; maia, jc; guimaraes, jt; calhau, c; taveira-gomes, a

See all (59)

Recommend this page Top
Copyright 1996-2025 © Faculdade de Medicina Dentária da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z
Page created on: 2025-08-07 at 21:02:47 | Privacy Policy | Personal Data Protection Policy | Whistleblowing | Electronic Yellow Book