Accuracy of prediction models for long-term type 2 diabetes remission after gastric bypass

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Cardoso, S (Author) Other; Pereira, SS (Author) ICBAS; Almeida, RF (Author) Other; Osorio, C (Author) Other; Silva, D (Author) Other; Nora, M (Author) Other; Monteiro, M (Author) ICBAS; Guimaraes, M (Author) Other

Journal

The Journal is awaiting validation by the Administrative Services.

Title: ACTA DIABETOLOGICA

Vol. 60

Pages: 1019-1026

ISSN: 0940-5429

Indexing

ISI Web of Knowledge - 0 Citations

Scopus

Other information

Authenticus ID: P-00Y-9Y9

DOI: 10.1007/s00592-023-02092-1

Abstract (EN): AimTo evaluate the accuracy of DiaBetter, DiaRem, Ad-DiaRem and 5y-Ad-DiaRem scores' at predicting T2D remission 10 or more years after surgery.MethodsPatients with obesity and T2D (n = 126) submitted to RYGB with 10 or more years of follow-up. It was a unicentric trial. Pre-operative anthropometric and clinical data was retrieved to calculate DiaRem, DiaBetter, Ad-DiaRem and 5y-Ad-DiaRem scores, while a hospital visit was conducted to assess current diabetes status. The area under the receiver operating characteristic (AUROC) curve was calculated as estimate of the scores' accuracy to predict long-term T2D remission.ResultsAmong the entire cohort (n = 126), 70 subjects (55.6%) achieved and maintained T2D remission 10 or more years after RYGB. The 5y-Ad-DiaRem score was the one that depicted the highest discriminative power (AUROC = 0.838) to predict long-term T2D remission when compared to DiaBetter (AUROC = 0.735), DiaRem (AUROC = 0.721) and Ad-DiaRem (AUROC = 0.720).ConclusionThe score with highest accuracy to predict long-term T2D remission after RYGB surgery was the 5y-Ad-DiaRem. Yet, the available scores accuracy to predict T2D remission in the long term is still suboptimal, highlighting the unmet need for a better scoring system.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8