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How Sustained is Roux-en-Y Gastric Bypass Long-term Efficacy?

Title
How Sustained is Roux-en-Y Gastric Bypass Long-term Efficacy?
Type
Article in International Scientific Journal
Year
2021
Authors
Guimarães, M
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Osório, C
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Silva, D
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Almeida, RF
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Reis, A
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Cardoso, S
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Pereira, SS
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Monteiro, M
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Nora, M
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Journal
Title: Obesity SurgeryImported from Authenticus Search for Journal Publications
Vol. 31 No. 8
Pages: 3623-3629
ISSN: 0960-8923
Publisher: Springer Nature
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Authenticus ID: P-00W-NT8
Abstract (EN): <jats:title>Abstract</jats:title><jats:sec> <jats:title>Purpose</jats:title> <jats:p>The rate of weight regain after Roux-en-Y Gastric Bypass (RYGB) can hamper the procedure long-term efficacy for obesity treatment and related comorbidities. To evaluate the rate of weight loss and comorbidity remission failure 10 years or more after RYGB surgery.</jats:p> </jats:sec><jats:sec> <jats:title>Materials and methods</jats:title> <jats:p>Retrospective observational cohort study. Patients submitted to RYGB for obesity treatment at a single centre with 10 years or more after surgery underwent a clinical reassessment.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Among the subjects invited for clinical revaluation (<jats:italic>n</jats:italic> = 585), only those who performed RYGB and attended the hospital visit were included in the study (<jats:italic>n</jats:italic> = 281). The pre-operative mean body mass index (BMI) was 44.4 ± 6.1 kg/m<jats:sup>2</jats:sup>. Mean post-operative time was 12.2 ± 1.1 years. After surgery, mean BMI was significantly lower 33.4 ± 5.8 kg/m<jats:sup>2</jats:sup> (<jats:italic>p</jats:italic> < 0.0001), 29.5% with a BMI < 30 kg/m<jats:sup>2</jats:sup>. Mean Total Weight Lost (%TWL) was 24.3 ± 11.4%, reaching a %TWL ¿ 20% in 70.1% with a mean %TWL of 30.0 ± 7.0%. Co-morbidities remission rate was 54.2% for type 2 diabetes, 34.1% for hypertension, 52.4% for hyperlipidemia and 50% for obstructive sleep apnea. Early complications rate was 13.2% and revision surgery occurred in 2.8% of patients. Four patients died of RYGB complications within the first 90 days after surgery.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>RYGB has a high rate of long-term successful weight loss and obesity-associated comorbidity improvement. Weight loss failure requiring revision surgery occurs in a small proportion of patients. Our data confirms the long-term effectiveness of RYGB as primary bariatric intervention.</jats:p> </jats:sec><jats:sec> <jats:title>Graphical abstract</jats:title> </jats:sec>
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 7
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