Multidrug-resistant high-risk Enterococcus faecium clones: can we really define them?

• Type: Another Publication in an International Scientific Journal
• Date: 2021

Authors

Freitas, AR (Author) Other; Pereira, AP (Author) Other; Novais, Carla (Author) FFUP; Luisa Peixe (Author) FFUP

Journal

Title: International Journal of Antimicrobial Agents

Vol. 57

ISSN: 0924-8579

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 1 Citation

Other information

Authenticus ID: P-00T-6R4

DOI: 10.1016/j.ijantimicag.2020.106227

Abstract (EN): Enterococcus faecium is a significant opportunistic human pathogen with a broad host range, including humans, farm animals, pets and wildlife. Specialised subpopulations have globally evolved towards a powerful and convergent adaption to the healthcare environment by acquiring a cocktail of key antimicrobial resistance and virulence genes, enabling them to thrive in the disturbed microbiota of hospitalised patients. These populations can also be found in different community reservoirs, but the relevance of their dispersal in non-human hosts is greatly unknown and is here discussed. This review provides a brief historical overview of what we have been considering E. faecium high-risk clones worldwide alongside the advances in strain typing technologies that have revolutionised our understanding of the genetic evolution of this species over the last three decades.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8