Physical characterization of hydroxyapatite porous scaffolds for tissue engineering

• Type: Article in International Scientific Journal
• Date: 2009

Authors

S. Teixeira (Author) FEUP; M. A. Rodriguez (Author) FEUP; P. Pena (Author) FEUP; A. H. de Aza (Author) FEUP; S. de Aza (Author) FEUP; Ferraz, MP (Author) FEUP; F. J. Monteiro (Author) FEUP

Journal

Title: Materials Science and Engineering C

Vol. 29 No. 5

Pages: 1510-1514

ISSN: 0928-4931

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 95 Citations

ISI Web of Science

Scopus - 106 Citations

INSPEC

Scientific classification

FOS: Engineering and technology > Other engineering and technologies

Other information

Authenticus ID: P-003-JV1

DOI: 10.1016/j.msec.2008.09.052

Abstract (EN): The present study refers to the preparation and characterization of porous hydroxyapatite scaffolds to be used as matrices for bone regeneration or as specific release vehicles. Ceramics are widely used for bone tissue engineering purposes and in this study, hydroxyapatite porous scaffolds were produced using the polymer replication method. Polyurethane sponges were used as templates and impregnated with a ceramic slurry at different ratios, and sintered at 1300 °C following a specific thermal cycle. The characteristics of the hydroxyapatite porous scaffolds and respective powder used as starting material, were investigated by using scanning electron microscopy, particle size distribution, X-ray diffraction, Fourier transformed infrared spectroscopy and compressive mechanical testing techniques. It was possible to produce highly porous hydroxyapatite scaffolds presenting micro and macropores and pore interconnectivity.

Language: English

Type (Professor's evaluation): Scientific