Placenta accreta risk-antepartum score in predicting clinical outcomes of placenta accreta spectrum: A multicenter validation study

• Type: Article in International Scientific Journal
• Date: 2021

Authors

Shazly, SA (Author) Other; Anan, MA (Author) Other; Makukhina, TB (Author) Other; Melekoglu, R (Author) Other; Ahmed, FU (Author) Other; Pinto, PV (Author) FMUP; Takahashi, H (Author) Other; Ahmed, NB (Author) Other; Sayed, EG (Author) Other; Elassall, GM (Author) Other; Said, AE (Author) Other; Fahmy, MS (Author) Other; Dawyee, DM (Author) Other; Penzhoyan, GA (Author) Other; Amirkhanyan, AM (Author) Other; Yilmaz, E (Author) Other; Celik, NZ (Author) Other; Aziz, H (Author) Other; Akhter, T (Author) Other; Ambreen, A (Author) Other; Abdelbadie, AS (Author) Other

Journal

Title: International Journal of Gynecology and Obstetrics

Vol. 158

Pages: 424-431

ISSN: 0020-7292

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00V-PWH

DOI: 10.1002/ijgo.13993

Abstract (EN): Objective To validate the use of placenta accreta risk-antepartum (PAR-A) score as a predictive tool of clinical outcomes of placenta accreta spectrum (PAS). Methods This is a prospective study, conducted in six PAS specialized centers in six different countries. The study was conducted between October 1, 2020 and March 31, 2021. Women who were provisionally diagnosed with PAS during pregnancy were considered eligible. A machine-learning-based PAR-A score was calculated. Diagnostic performance of the PAR-A score was evaluated using a receiver operating characteristic curve, for perioperative massive blood loss and admission to intensive care unit (ClinicalTrials.gov identifier NCT04525001). Results Of 97 eligible women, 86 were included. PAS-associated massive blood loss occurred in 10 patients (11.63%). Median PAR-A scores of massive blood loss in the current cohort were 8.9 (interquartile range 6.9-14.1). In predicting massive blood loss, the area under the curve of PAR-A scores was 0.85 (95% confidence interval [CI] 0.74-0.95), which was not significantly different from the original cohort (P = 0.2). PAR-A score prediction of intensive care unit admission was slightly higher compared with the original cohort (0.88, 95% CI 0.81-0.95; P = 0.06). Conclusion PAR-A score is a novel scoring system of PAS outcomes, which showed external validity based on current data.

Language: English

Type (Professor's evaluation): Dissemination

No. of pages: 8