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The interplay of leukemia cells and the bone marrow microenvironment

Title
The interplay of leukemia cells and the bone marrow microenvironment
Type
Another Publication in an International Scientific Journal
Year
2018
Authors
Duarte, D
(Author)
FMUP
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Hawkins, ED
(Author)
Other
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Lo Celso, C
(Author)
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Journal
Title: BloodImported from Authenticus Search for Journal Publications
Vol. 131
Pages: 1507-1511
ISSN: 0006-4971
Publisher: Elsevier
Indexing
Other information
Authenticus ID: P-00T-90X
Abstract (EN): The interplay of cancer cells and surrounding stroma is critical in disease progression. This is particularly evident in hematological malignancies that infiltrate the bone marrow and peripheral lymphoid organs. Despite clear evidence for the existence of these interactions, the precise repercussions on the growth of leukemic cells are poorly understood. Recent development of novel imaging technology and preclinical disease models has advanced our comprehension of leukemia-microenvironment crosstalk and has potential implications for development of novel treatment options. © 2018 by The American Society of Hematology.
Language: English
Type (Professor's evaluation): Scientific
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