Abstract (EN):
<jats:sec id="S092493382101141X_sec6437" sec-type="intro"><jats:title>Introduction</jats:title><jats:p>Neuropsychiatric symptoms (NPS) are common, disabling and burdensome core-features of dementia, with important diagnostic and prognostic value. However, their measurement remains challenging. The Neuropsychiatric Inventory (NPI) is the most widely used NPS measure. Nevertheless, it is also time-consuming and impractical in most clinical settings. Therefore, the Abe¿s BPSD score (ABS) has been proposed as a brief score to facilitate the NPS assessment.</jats:p></jats:sec><jats:sec id="S092493382101141X_sec6438"><jats:title>Objectives</jats:title><jats:p>To explore the concurrent validity of the Portuguese ABS by comparing the 10 ABS items with the relevant NPI-12 domains.</jats:p></jats:sec><jats:sec id="S092493382101141X_sec6439" sec-type="methods"><jats:title>Methods</jats:title><jats:p>A cross-sectional study was conducted with outpatients attending a gerontopsychiatric consultation. Patients were included if they were ¿65 years and had a reliable caregiver. NPS frequency rates (number of patients with a symptom) were estimated with ABS and NPI-12, and an agreement analysis was undertaken by calculating kappa-coefficients (k) and the respective 95% confidence interval [95%CI] between ABS items and relevant NPI-12 domains.</jats:p></jats:sec><jats:sec id="S092493382101141X_sec6440" sec-type="results"><jats:title>Results</jats:title><jats:p>Overall, 107 patients were included. Kappa-values ranged from 0.277 to 1.000. Higher agreement was recorded for the ABS items eating/toilet problems (k=1.000), day¿night reversal (k=0.976[0.925-1.000]) and depressive/gloomy mood (k=0.957[0.899-1.000]), with the NPI-12 appetite/eating abnormalities, night-time behavioural disturbances and dysphoria domains, respectively. The ABS item violent force recorded the lowest agreement (k=0.277[0.104-0.45]) with the NPI-12 agitation/aggression domain.</jats:p></jats:sec><jats:sec id="S092493382101141X_sec6441" sec-type="conclusions"><jats:title>Conclusions</jats:title><jats:p>This exploratory analysis demonstrates good levels of agreement between most ABS items and relevant NPI-12 domains. Data add to the evidence that both measures capture a comparable broad spectrum of psychopathology, supporting the ABS use in clinical routine. Support: FCT(PD/BD/114555/2016), and National Funds through FCT-within CINTESIS, R&D Unit (ref.UIDB/4255/2020).</jats:p></jats:sec>
Language:
English
Type (Professor's evaluation):
Scientific