Autoimmune progesterone dermatitis: Case report of an unexpected treatment reaction

• Type: Article in International Scientific Journal
• Date: 2017

Authors

Camoes, S (Author) Other; Sampaio, J (Author) Other; Rocha, J (Author) Other; Tiago, P (Author) Other; Lopes, C (Author) FMUP

Journal

The Journal is awaiting validation by the Administrative Services.

Title: AUSTRALASIAN JOURNAL OF DERMATOLOGY

Vol. 58

Pages: E132-E134

ISSN: 0004-8380

Publisher: Wiley

Indexing

ISI Web of Knowledge - 4 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-00M-52D

DOI: 10.1111/ajd.12529

Abstract (EN): Autoimmune progesterone dermatitis (APD) is a rare skin condition with a varying morphology, which appears on a monthly basis during the luteal phase of the menstrual cycle and resolves spontaneously with the endogenous decrease in progesterone during menses. We present the case of 39-year-old multiparous Caucasian woman with generalised, self-limited urticaria in her perimenstrual period. APD was diagnosed in light of the cyclical nature of the symptoms. An intradermal test with the administration of 0.5 mg/mL of medroxyprogesterone acetate showed a positive result. She started using vaginal hormonal contraceptive that paradoxically exacerbate the symptoms, which ceased after the removal of the device. An oral combined contraceptive was initiated instead, with complete resolution of the symptoms. We share the case because of the rarity of the situation, emphasising the importance of a multidisciplinary team for differential diagnosis and patient follow up.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3