Complete mole in a dichorionic twin pregnancy after intracytoplasmic sperm injection [Mola hidatiforme completa em gravidez bicoriônica após injecção intracitoplasmática de espermatozoides]

• Type: Article in International Scientific Journal
• Date: 2013

Authors

Ferraz, TJSM (Author) Other; Bartosch, CMM (Author) Other; ramalho, c (Author) FMUP; carvalho, f (Author) FMUP; de Carvalho, BCCL (Author) Other; Brandao, OGBC (Author) Other; Montenegro N (Author) FMUP

Journal

Title: Revista Brasileira de Ginecologia e Obstetricia

Vol. 35

Pages: 39-43

ISSN: 0100-7203

Publisher: Thieme

Indexing

Scopus - 12 Citations

Other information

Authenticus ID: P-008-8TJ

DOI: 10.1590/s0100-72032013000100008

Abstract (EN): A dichorionic twin pregnancy with complete hydatidiform mole and coexistent fetus is a rare and challenging situation, whose pathogenesis has not been yet fully understood. We present a case of a 39-year-old woman who underwent intracytoplasmic sperm injection with two embryos transfer. The 12-week gestation ultrasound examination revealed normal fetus and placenta with features of hydatidiform mole, leading to pregnancy termination. Autopsy and histological examinations diagnosed a complete mole coexisting with a normal fetus, and the genetic analysis showed a diploid fetus with biparental genome and molar tissue with paternal diploidy. This case highlighted that complete molar pregnancies may still occur even though pregnancy is achieved after intracytoplasmic sperm injection. A review of the literature was performed by collecting data from the few similar reported cases and by commenting on the pathogenesis of this rare condition.

Language: English

Type (Professor's evaluation): Scientific