Biological activity of two glass ceramics in the meta- and pyrophosphate region: a comparative study

• Type: Article in International Scientific Journal
• Date: 2004

Authors

Anabela G. Dias (Author) Other; Maria Adelina Costa (Author) ICBAS; Maria Ascensão Lopes (Author) FEUP; José Domingos Santos (Author) FEUP; M. H. Fernandes (Author) Other

Journal

The Journal is awaiting validation by the Administrative Services.

Title: BIOCERAMICS, VOL 16

Vol. 254-256

Pages: 825-828

Indexing

ISI Web of Knowledge - 5 Citations

ISI Web of Science

Scopus - 5 Citations

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

Other information

Authenticus ID: P-000-CBN

DOI: 10.4028/www.scientific.net/kem.254-256.825

Abstract (EN): Based upon the CaO-P2O5 glass system, two glass ceramics were prepared in the meta- and pyrophosphate regions. The present work describes preliminary results concerning the biological activity of MK5B (45CaO-45P(2)O(5)-5MgO-5K(2)O, in mol %) and MT13B (45CaO-37P(2)O(5)-5MgO-13TiO(2), in mol %) using MG63 osteoblast-like cells. Both materials supported cell growth and proliferation which increased with the incubation time. However, cell growth was significantly lower on seeded MK5B samples. SEM observation showed that cell adhesion and spreading were hampered on this material. Evident degradation of the material surface was observed with simultaneous cell proliferation and material precipitation. By contrast, MT13B presented a relatively stable surface throughout the culture time. Results suggest that the in vitro biological behaviour of MK5B and MT13B is related with differences in the degradation rates of the two materials during the culture time.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4