Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads

• Type: Article in International Scientific Journal
• Date: 1999

Authors

Barros, RM (Author) Other; F. Xavier Malcata (Author) Other

Journal

Title: Bioprocess Engineering

Vol. 20 No. 4

Pages: 101-104

ISSN: 0178-515X

Publisher: Springer

Indexing

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Other information

Authenticus ID: P-001-588

DOI: 10.1007/s004490050566

Abstract (EN): Application of Fick's first law to substrate undergoing chemical reaction catalyzed by an enzyme immobilized in a porous slab-shaped bead leads to substrate concentration profiles that are flatter when the ratio of stoichiometric coefficients of product to reactant (v) is lower. Since the actual effectiveness factor decreases when v increases (at approximately the same rate irrespective of the value taken by the Michaelis-Menten parameter). then considerable overprediction of the conversion levels obtained within a given reaction timeframe will occur if the simplistic land more easily modelled) situation of equimolar counterdiffusion is taken for modelling purposes when v>1.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4