NUCLEAR-BODIES IN THE NORMAL AND HYPERFUNCTIONAL HUMAN ADRENAL-CORTEX

• Type: Article in International Scientific Journal
• Date: 1989

Authors

MAGALHAES, MM (Author) Other; Carvalho, Davide (Author) FMUP; OLIVEIRA, MA (Author) Other; MAGALHAES, MC (Author) Other

Journal

Title: Histology and Histopathology

Vol. 4

Pages: 241-245

ISSN: 0213-3911

Publisher: Plaza Fuensanta

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 2 Citations

Other information

Authenticus ID: P-001-SXD

Abstract (EN): Adrenal pieces obtained from six female patients, three without increased adrenocortical function and three with Cushing's disease, showed, in all adrenal cortex zones, cells containing simple and complex nuclear bodies. The simple nuclear bodies were spherical or ovoid and had a filamentous structure surrounded by a clear halo. Complex nuclear bodies were more numerous and heterogeneous in patients with adrenal pathology, and they were spherical with a proteinaceous filamentous capsule surrounding a core; the core was granular, filamentous or a mixture of granular and filamentous material, sometimes with a reticular or concentric arrangement. Some bodies showed vacuolar or multilocular aspect, and others had a close relationship with the nucleolus or appeared near the interchromatin granules. The meaning of adrenal nuclear bodies is discussed as well as their relationship with ACTH stimulation.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5