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Bonelike((R))/PLGA hybrid materials for bone regeneration: In vivo evaluation

Title
Bonelike((R))/PLGA hybrid materials for bone regeneration: In vivo evaluation
Type
Article in International Scientific Journal
Year
2004
Authors
Oliveira, JM
(Author)
Other
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Kawai, T
(Author)
Other
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Lopes, MA
(Author)
FEUP
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Ohtsuki, C
(Author)
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Santos, JD
(Author)
FEUP
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Américo Afonso
(Author)
FMDUP
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Publicação em ISI Web of Science ISI Web of Science
Scientific classification
FOS: Engineering and technology > Materials engineering
CORDIS: Technological sciences > Engineering > Biomaterial engineering
Other information
Authenticus ID: P-000-C3E
Abstract (EN): The biocompatibility and osteoconductive potential of Bonelike(R) and Bonelike(R)/PLGA hybrid materials were evaluated through subcutaneous and tibiae implantations for a 4 week period. Qualitative histology was performed to evaluate new bone formation and characterise bone-implant interface and results showed that Bonelike(R)/PLGA hybrid materials promote extensive bone growth. After the 4 week implantation period, Bonelikee resorption was recognized, which may be due to the presence of resorbable beta and alpha-tricalcium phosphate phases.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 4
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