Partially Reversible Cardiomyopathy after Renal Transplant Associated with Anti-Troponin I Antibodies

• Type: Another Publication in an International Scientific Journal
• Date: 2013

Authors

José Pedro Nunes (Author) FMUP; Faria, MD (Author) Other; Sampaio, S (Author) Other; Quintas, J (Author) Other; Katus, HA (Author) Other; Kaya, Z (Author) Other

Journal

Title: Cardiology

Vol. 126 No. 3

Pages: 173-174

ISSN: 0008-6312

Publisher: Karger

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 5 Citations

Other information

Authenticus ID: P-008-HDC

DOI: 10.1159/000353262

Abstract (EN): Cardiomyopathy associated with dialysis has been shown to be reversible in some cases. A 58-year-old female patient with polycystic renal disease and end-stage renal disease had a renal transplant after 9 years on hemodialysis. Dilated cardiomyopathy with depressed left ventricular ejection fraction markedly improved after transplantation, with normalization of the ejection fraction. High titers for anti-troponin 1 antibodies were measured: IgG 1:640, IgM 1:80. In our case, the presence of anticardiac (anti-troponin I) antibodies may suggest that the syndrome of reversible cardiomyopathy seen after renal transplantation is associated with immunosuppression therapy acting on immunological mechanisms previously at play. (C) 2013 S. Karger AG, Basel

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 2