Biomarkers for Bladder Pain Syndrome/Interstitial Cystitis

• Type: Article in International Scientific Journal
• Date: 2021

Authors

Charrua A. (Author) FMUP; Mendes, P (Author) FMUP; Cruz C.D. (Author) FMUP

Journal

Title: Current Bladder Dysfunction Reports

Vol. 16

Pages: 12-18

ISSN: 1931-7212

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 1 Citation

Other information

Authenticus ID: P-00T-A85

DOI: 10.1007/s11884-020-00626-9

Abstract (EN): Purpose of Review In this manuscript, the literature published in the past 5 years about BPS/IC biomarkers was reviewed. Topics include BPS/IC biomarkers, the classical BPS/IC diagnostic, clinical outcomes as a new concept of BPS/IC phenotyping biomarkers, BPS/IC urinary biomarkers, BPS/IC bladder tissue biomarkers and BPS/IC biomarkers outside the bladder. Recent Findings The importance of patients' phenotyping and sub-grouping emerged as a way of finding new BPS/IC biomarkers and treatment. Also, the use of non-invasive methodologies and of artificial intelligence approaches has been gaining momentum in BPS/IC biomarkers studies. Biomarker research points to the need of following an approach based on a systemic theory instead of a bladder-centred theory. Also, the importance of sample size and the choice of controls to validate BPS/IC biomarkers have been elevated.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7