Case Report: Mastocytosis: The Long Road to Diagnosis

• Type: Another Publication in an International Scientific Journal
• Date: 2021

Authors

Tiago Rama (Author) FMUP; Martins, D (Author) Other; Gomes, N (Author) Other; Pinheiro, J (Author) Other; Nogueira, A (Author) Other; Delgado, L (Author) FMUP; Placido, JL (Author) Other; Coimbra, A (Author) Other

Journal

Title: Frontiers In Immunology

ISSN: 1664-3224

Publisher: Frontiers Media

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 2 Citations

Other information

Authenticus ID: P-00T-ET2

DOI: 10.3389/fimmu.2021.635909

Abstract (EN): Mastocytosis is a heterogeneous group of disorders characterized by expansion and accumulation of clonal mast cells. Patients mainly present with either cutaneous lesions, anaphylaxis, or both. Its low prevalence and unusual features often hinder its diagnosis for several years. We report the case of an 18-year-old male who was referred to our department with a long-standing history of atypical skin lesions, allergic rhinitis, exercise-induced bronchoconstriction and what was believed to be food-related flushing and anaphylaxis, that was later diagnosed with mastocytosis. This case illustrates the need to consider investigating for mastocytosis when recurrent anaphylaxis is present, especially in the presence of atypical skin lesions, even if normal serum basal tryptase levels and allergic sensitization are present.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5