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Placentation-related processes in a human first-trimester extravillous trophoblast cell line (HTR-8/SVneo cells) are affected by several xenobiotics

Title
Placentation-related processes in a human first-trimester extravillous trophoblast cell line (HTR-8/SVneo cells) are affected by several xenobiotics
Type
Article in International Scientific Journal
Year
2019
Authors
Correia Branco, A
(Author)
Other
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Elisa Keating
(Author)
FMUP
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Martel, F
(Author)
FMUP
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Journal
Vol. 42
Pages: 541-545
ISSN: 0148-0545
Publisher: Taylor & Francis
Other information
Authenticus ID: P-00Q-TQM
Resumo (PT):
Abstract (EN): Our aim was to investigate the effect of some xenobiotics on placentation-related processes in an extravillous trophoblastic cell line (HTR-8/SVneo cells). Amphetamine, MDMA, theophylline, and fluoxetine, but not nicotine, cocaine, and caffeine, had a negative effect on cell proliferation rates, culture growth, viability, or migratory capacity. These compounds have a detrimental effect in placentation-related processes of HTR-8/SVneo cells.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 5
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