Revisiting Amniotic Band Sequence: A Wide Spectrum of Manifestations

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Barros, M (Author) Other; Gorgal, G (Author) Other; Machado, AP (Author) Other; ramalho, c (Author) FMUP; matias, a (Author) FMUP; Montenegro, N (Author) Other

Journal

Title: Fetal Diagnosis and Therapy

Vol. 35

Pages: 51-56

ISSN: 1015-3837

Publisher: Karger

Indexing

ISI Web of Knowledge - 12 Citations

Scopus - 16 Citations

Other information

Authenticus ID: P-009-6JC

DOI: 10.1159/000354616

Abstract (EN): Objective: To describe the spectrum of clinical deformities related to amniotic band sequence (ABS), ranging from mild to severe. Methods: Retrospective evaluation of 9 cases of ABS managed during a 4-year period (February 2006 to April 2010) in a tertiary hospital. Results: The median gestational age at prenatal diagnosis was 15 weeks (range 11-26). Only 2 patients had clinical prenatal evidence of amnion rupture. In the other 5 cases the diagnosis of ABS was established prenatally based on fetal structural abnormalities. These abnormalities included: (1) upper limb defects: syndactyly, amputation at the level of phalanges or first metacarpal or forearm; (2) inferior extremities defects: tallus equinovarus and flexed knee, and constriction ring; (3) umbilical cord strangulation, and (4) acrania. Conclusion: ABS is a polymorphous syndrome and recognizing its various manifestations can be of help in prenatal identification. (C) 2013 S. Karger AG, Basel

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6