Magnetron co-sputtered TiO2/SiO2/Ag nanocomposite thin coatings inhibiting bacterial adhesion and biofilm formation

• Type: Article in International Scientific Journal
• Date: 2020-01-02

Authors

Todorka Vladkova (Author) Other; Orlin Angelov (Author) Other; Dragomira Stoyanova (Author) Other; Dilyana Gospodinova (Author) Other; Luciana Gomes (Author) FEUP; Alexandra Soares (Author) Other; Filipe Mergulhão (Author) FEUP; Iliana Ivanova (Author) Other

Journal

Title: Surface and Coatings Technology

Vol. 384

ISSN: 0257-8972

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-00R-HZC

DOI: 10.1016/j.surfcoat.2019.125322

Abstract (EN): Aim of this study is the development of new functional coatings for medical devices, using magnetron co-sputtering to deposit triple TiO2/SiO2/Ag nanocomposite thin films with expected antimicrobial activity. Some surface characteristics (elemental composition, hydrophilic/hydrophobic balance, surface energy and topography) were estimated to look for correlation with bacterial cells growth and biofilm formation on TiO2/SiO2/Ag coated samples. Strong inhibitory effect toward Escherichia coli growth was found: the number of viable bacterial cells approaches to zero at the first 30 min -1 h, depending on the Ag content. Biofilm formation in urine flow at 48 h is reduced down to 92% compared to a control glass surface. Direct contact and eluted silver mediated killing were experimentally demonstrated as mechanisms of antibacterial action of the TiO2/SiO2/Ag coatings. These coatings are promising candidate for antimicrobial protection of urinary tract devices for at least 48 h, suggesting benefits over longer time.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7