Quorum sensing inhibition by marine bacteria

• Type: Article in International Scientific Journal
• Date: 2019

Authors

Anabela Borges (Author) FEUP; Manuel Simões (Author) FEUP

Journal

Title: Marine Drugs

Vol. 17 No. 7

Pages: 1-25

ISSN: 1660-3397

Publisher: MDPI

Indexing

ISI Web of Knowledge - 0 Citations

ISI Web of Science

Scopus - 18 Citations

Associated Projects

ALGAVALOR - MicroALGAs: produção integrada e VALORização da biomassa e das suas diversas aplicações

LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia

LEPABE-2-ECO-INNOVATION - LEPABE-2-ECO-INNOVATION

Other information

Authenticus ID: P-00Q-WEB

DOI: 10.3390/md17070427

Abstract (EN): Antibiotic resistance has been increasingly reported for a wide variety of bacteria of clinical significance. This widespread problem constitutes one of the greatest challenges of the twenty-first century. Faced with this issue, clinicians and researchers have been persuaded to design novel strategies in order to try to control pathogenic bacteria. Therefore, the discovery and elucidation of the mechanisms underlying bacterial pathogenesis and intercellular communication have opened new perspectives for the development of alternative approaches. Antipathogenic and/or antivirulence therapies based on the interruption of quorum sensing pathways are one of several such promising strategies aimed at disarming rather than at eradicating bacterial pathogens during the course of colonization and infection. This review describes mechanisms of bacterial communication involved in biofilm formation. An overview of the potential of marine bacteria and their bioactive components as QS inhibitors is further provided.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 25