The First Transthyretin Familial Amyloid Polyneuropathy Gait Quantification Study - Preliminary Results

• Type: Article in International Conference Proceedings Book
• Date: 2017

Authors

Vilas Boas, MD (Author) Other; Rocha, AP (Author) Other; Pereira Choupina, HMP (Author) Other; Fernandes, JM (Author) Other; Coelho, T (Author) Other; Cunha, JPS (Author) FEUP

Conference proceedings International

Title: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Pages: 1368-1371

39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017

11 July 2017 through 15 July 2017

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 5 Citations

Other information

Authenticus ID: P-00N-56R

DOI: 10.1109/embc.2017.8037087

Abstract (EN): Transthyretin Familial Amyloid Polyneuropathy (TTR-FAP) is a rare neurological disease caused by a genetic mutation with a variable presentation and consequent challenging diagnosis, complex follow-up and treatment. At this moment, this condition has no cure and treatment options are under development. One of the disease's implications is a definite and progressive motor impairment that from the early stages compromises walking ability and daily life activities. The detection of this impairment is key for the disease onset diagnosis. With the goal of improving diagnosis of the symptoms and patients' quality of life, the authors have assessed the gait characteristics of subjects suffering from this condition. This contribution shows the results of a preliminary study, using a non-intrusive, markerless vision-based gait analysis tool. To the best of our knowledge, the reported results constitute the first gait analysis data of TTR-FAP mutation carriers.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4