Helicobacter heilmannii sensu lato: An overview of the infection in humans

• Type: Another Publication in an International Scientific Journal
• Date: 2014

Authors

Bento Miranda, M (Author) Other; Figueiredo C (Author) FMUP

Journal

Title: World Journal of Gastroenterology

Vol. 20

ISSN: 1007-9327

Publisher: Baishideng Publishing Group

Indexing

ISI Web of Knowledge - 29 Citations

Scopus - 33 Citations

Other information

Authenticus ID: P-00A-233

DOI: 10.3748/wjg.v20.i47.17779

Abstract (EN): Helicobacter heilmannii sensu lato (H. heilmannii s.l.) is a group of gastric non-Helicobacter pylori Helicobacter species that are morphologically indistinguishable from each other. H. heilmannii s.l. infect the stomach of several animals and may have zoonotic potential. Although the prevalence of these infections in humans is low, they are associated with gastric pathology, including mucosa-associated lymphoid tissue lymphoma, making them a significant health issue. Here, the taxonomy, epidemiology, microbiology, diagnosis, and treatment of these infections will be reviewed. The gastric pathology associated with H. heilmannii s.l. infections in humans will also be addressed. Finally, the features of the complete bacterial genomes available and studies on species-specific pathogenesis will be reviewed. The understanding of the mechanisms that underlie gastric disease development mediated by the different bacterial species that constitute H. heilmannii s.l. is essential for developing strategies for prevention and treatment of these infections.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9