Go to:
Logótipo
Você está em: Start > Publications > View > Life course path analysis of total and central adiposity throughout adolescence on adult blood pressure and insulin resistance
Map of Premises
Principal
Publication

Life course path analysis of total and central adiposity throughout adolescence on adult blood pressure and insulin resistance

Title
Life course path analysis of total and central adiposity throughout adolescence on adult blood pressure and insulin resistance
Type
Article in International Scientific Journal
Year
2017
Authors
Araujo, J
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Severo M
(Author)
FMUP
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page Without ORCID
Santos, S
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Ramos, E
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Journal
Vol. 27
Pages: 360-365
ISSN: 0939-4753
Publisher: Elsevier
Other information
Authenticus ID: P-00M-SEK
Abstract (EN): Background and aim: We aimed to study whether the effect of adolescent adiposity on adult blood pressure and insulin resistance was mediated by adult adiposity. Methods and results: Data from the EPITeen cohort at 13, 17 and 21 years was used (n = 2211). Sex- and age-specific body mass index z-scores (BMIz) and waist-to-hip ratio (WHR) were used as indicators of total and central adiposity, respectively. Systolic blood pressure (SBP), glucose and insulin were assessed at 21 years and the homeostasis model assessment (HOMA-IR) was used as a marker of insulin resistance. Path analysis was applied to evaluate direct and indirect effects of adiposity (13, 17 and 21y) on adult SBP and HOMA-IR, separately for total and central adiposity and for each outcome. Results are presented as standardized regression coefficients [beta (95%CI)]. The total effect of BMIz at 13 years on SBP at 21 years was 0.211 (0.178; 0.244), totally mediated by adult BMIz. Total effect of BMIz 13y on HOMA-IR was 0.248 (0.196; 0.299). Although this effect was mostly mediated by BMIz 21y, an additional direct effect from BMIz 17y was found [beta = -0.240 (-0.315; -0.164)]. Central adiposity was also positively associated with SBP and HOMA-IR at 21 years, and the effect of adolescent WHR was totally mediated by adult WHR for both outcomes. Conclusions: The effect of adolescent adiposity on adult SBP and HOMA-IR was mostly mediated by adult adiposity. However, for HOMA-IR an additional direct effect from total adiposity at 17 years was found.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 6
Documents
We could not find any documents associated to the publication.
Related Publications

Of the same authors

Proceedings of the 3rd IPLeiria's International Health Congress Abstracts (2016)
Article in International Scientific Journal
Tomás, CC; Oliveira, E; Sousa, D; Uba Chupel, M; Furtado, G; Rocha, C; Lopes C; Ferreira, P; Alves, C; Gisin, S; Catarino, E; Carvalho, N; Coucelo, T; Bonfim, L; Silva, C; Franco, D; González, JA; Jardim, HG; Silva, R; Baixinho, CL...(mais 1673 authors)

Of the same journal

The role of prenatal exposures on body fat patterns at 7 years: Intrauterine programming or birthweight effects? (2016)
Article in International Scientific Journal
Santos, S; Severo M; Gaillard, R; Santos, AC; Barros, H; Oliveira, A
The lymphocyte-to-monocyte ratio: An added value for death prediction in heart failure (2015)
Article in International Scientific Journal
Silva, N; Bettencourt P; guimaraes, jt
Muscular fitness, adherence to the Southern European Atlantic Diet and cardiometabolic risk factors in adolescents (2017)
Article in International Scientific Journal
C. Agostinis-Sobrinho; S. Abreu; C. Moreira; L. Lopes; A. García-Hermoso; R. Ramírez-Vélez; J.E. Correa-Bautista; J. Mota; R. Santos
Metabolically healthy overweight in young adulthood: is it a matter of duration and degree of overweight? (2021)
Article in International Scientific Journal
Craveiro, V; Ramos E; Araujo, J
Longitudinal association of adiposity and high-sensitivity C-reactive protein from adolescence into early adulthood (2019)
Article in International Scientific Journal
Cabral, M; Severo M; Barros H; guimaraes, jt; Ramos E

See all (25)

Recommend this page Top
Copyright 1996-2025 © Faculdade de Medicina Dentária da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z
Page created on: 2025-07-26 at 01:37:01 | Privacy Policy | Personal Data Protection Policy | Whistleblowing | Electronic Yellow Book