Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems

• Type: Another Publication in an International Scientific Journal
• Date: 2017

Authors

Granja, A (Author) Other; Frias, I (Author) Other; Neves, AR (Author) Other; Pinheiro, M (Author) Other; Salette Reis (Author) FFUP

Journal

Title: BioMed Research International

Vol. 2017

Pages: 1-15

ISSN: 2314-6133

Publisher: Hindawi

Indexing

ISI Web of Knowledge - 18 Citations

Scopus - 51 Citations

Other information

Authenticus ID: P-00N-G7J

DOI: 10.1155/2017/5813793

Abstract (EN): Nowadays, the society is facing a large health problem with the rising of new diseases, including cancer, heart diseases, diabetes, neurodegenerative diseases, and obesity. Thus, it is important to invest in substances that enhance the health of the population. In this context, epigallocatechin gallate (EGCG) is a flavonoid found in many plants, especially in tea. Several studies support the notion that EGCG has several benefits in fighting cancer, heart diseases, diabetes, and obesity, among others. Nevertheless, the poor intestinal absorbance and instability of EGCG constitute the main drawback to use this molecule in prevention and therapy. The encapsulation of EGCG in nanocarriers leads to its enhanced stability and higher therapeutic effects. A comprehensive review of studies currently available on the encapsulation of EGCG by means of nanocarriers will be addressed.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 15