Obesity vaccines

• Type: Another Publication in an International Scientific Journal
• Date: 2014

Authors

Monteiro, M (Author) ICBAS

Journal

The Journal is awaiting validation by the Administrative Services.

Title: HUMAN VACCINES & IMMUNOTHERAPEUTICS

Vol. 10

Pages: 887-895

ISSN: 2164-5515

Publisher: Landes Bioscience

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 9 Citations

Other information

Authenticus ID: P-009-HZW

DOI: 10.4161/hv.27537

Abstract (EN): Obesity is one of the largest and fastest growing public health problems in the world. Last century social changes have set an obesogenic milieu that calls for micro and macro environment interventions for disease prevention, while treatment is mandatory for individuals already obese. The cornerstone of overweight and obesity treatment is diet and physical exercise. However, many patients find lifestyle modifications difficult to comply and prone to failure in the long-term; therefore many patients consider anti-obesity drugs an important adjuvant if not a better alternative to behavioral approach or obesity surgery. Since the pharmacological options for obesity treatment remain quite limited, this is an exciting research area, with new treatment targets and strategies on the horizon. This review discusses the development of innovative therapeutic agents, focusing in energy homeostasis regulation and the use of molecular vaccines, targeting hormones such as somatostatin, GIP and ghrelin, to reduce body weight.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9