Enantioseparation of chiral pharmaceuticals in biomedical and environmental analyses by liquid chromatography: An overview

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Ana Rita Ribeiro (Author) FEUP; Alexandra S. Maia (Author) Other; Quezia B. Cass (Author) Other; Maria Elisabeth Tiritan (Author) FFUP

Journal

Title: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Vol. 968

Pages: 8-21

ISSN: 1570-0232

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 92 Citations

Scopus - 96 Citations

Other information

Authenticus ID: P-009-TG9

DOI: 10.1016/j.jchromb.2014.02.049

Abstract (EN): This review aims to present the issues associated to enantioseparation of chiral pharmaceuticals in biological and environmental matrices using chiral stationary phases (CSP). Thus, it related some enantioselective methods in liquid chromatography (LC) and compares the importance given to chiral separation in biomedical and environmental fields. For that the most used CSP, the enantioselective chromatographic methods, their advantages and drawbacks were swiftly revised and compared. The recent advances and the limitations of chiral analytical methods in LC were also discussed.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 14