DISTRIBUTION OF GLOMERULI WITH FLUORIDE-RESISTANT ACID-PHOSPHATASE (FRAP)-CONTAINING TERMINALS IN THE SUBSTANTIA GELATINOSA OF THE RAT

• Type: Article in International Scientific Journal
• Date: 1986

Authors

RIBEIRODASILVA, A (Author) Other; Castro-Lopes J.M. (Author) FMUP; COIMBRA, A (Author) Other

Journal

Title: Brain Research

Vol. 377

Pages: 323-329

ISSN: 0006-8993

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 42 Citations

Scopus - 44 Citations

Other information

Authenticus ID: P-001-VRH

DOI: 10.1016/0006-8993(86)90875-9

Abstract (EN): In the cervical enlargement of the rat spinal cord, fluoride-resistant acid phosphatase (FRAP) occurs in most of the small dark sinuous primary afferent central terminals (C(I)-terminals) of type I-synaptic glomeruli of lamina II and is lacking in the large light roundish primary afferent C(II)-terminals of type II-glomeruli. Reactive C(I)-terminals are heterogeneously distributed across the dorsoventral thickness of lamina II, with maximal frequency in the zone heavily stained for FRAP in light micrographs, which roughly corresponds to the dorsalmost portion of lamina IIi. In the rest of lamina II many C(I)-terminals do not contain FRAP. Since all C(I)-terminals appear to originate from unmyelinated, presumably nociceptive, primary afferents, it is proposed that the FRAP-reactive ones arise from the FRAP-containing subpopulation of DRG small cells, while those lacking FRAP, which have a distinct area of termination in the dorsal horn, belong to the peptide-containing subpopulation.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7