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INTRANUCLEAR CYTOPLASMIC INCLUSIONS IN THYROID PAPILLARY CARCINOMAS

Title
INTRANUCLEAR CYTOPLASMIC INCLUSIONS IN THYROID PAPILLARY CARCINOMAS
Type
Article in International Scientific Journal
Year
1980
Authors
GONCALVES, V
(Author)
Other
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Sobrinho Simoes, M
(Author)
FMUP
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Journal
Vol. 12
Pages: 137-143
ISSN: 1122-9497
Other information
Authenticus ID: P-001-YHX
Abstract (EN): Some ultrastructural features of intranuclear cytoplasmic inclusions (ICI) were studied in 25 thyroid papillary carcinomas. Most of ICIs appear to be true nuclear inclusions and are frequently filled with M bodies and microfilaments. Their content suffers a sequential decomposition process similar to focal cytoplasmic degradation, but acid phosphatase activity could not be detected. A hypothesis is advanced on the rough endoplasmic reticulum origin of M bodies and the important role played by microfilaments in the genesis of ICIs.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 7
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