Go to:
Logótipo
Você está em: Start > Publications > View > Determinants of frailty: the added value of assessing medication
Map of Premises
Principal
Publication

Determinants of frailty: the added value of assessing medication

Title
Determinants of frailty: the added value of assessing medication
Type
Article in International Scientific Journal
Year
2015
Authors
Coelho, T
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Constança Paúl
(Author)
ICBAS
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page View ORCID page
Gobbens, RJJ
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Lia Fernandes
(Author)
FMUP
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page View ORCID page
Journal
Vol. 7
ISSN: 1663-4365
Publisher: Frontiers Media
Other information
Authenticus ID: P-00A-D5Z
Abstract (EN): This study aims to analyze which determinants predict frailty in general and each frailty domain (physical, psychological, and social), considering the integral conceptual model of frailty, and particularly to examine the contribution of medication in this prediction. A cross-sectional study was designed using a non-probabilistic sample of 252 community-dwelling elderly from three Portuguese cities. Frailty and determinants of frailty were assessed with the Tilburg Frailty Indicator. The amount and type of different daily-consumed medication were also examined. Hierarchical regression analysis were conducted. The mean age of the participants was 79.2 years (+/- 7.3), and most of them were women (75.8%), widowed (55.6%) and with a low educational level (0-4 years: 63.9%). In this study, determinants explained 46% of the variance of total frailty, and 39.8, 25.3, and 27.7% of physical, psychological, and social frailty respectively. Age, gender, income, death of a loved one in the past year, lifestyle, satisfaction with living environment and self-reported comorbidity predicted total frailty, while each frailty domain was associated with a different set of determinants. The number of daily-consumed drugs was independently associated with physical frailty, and the consumption of medication for the cardiovascular system and for the blood and blood-forming organs explained part of the variance of total and physical frailty. The adverse effects of polymedication and its direct link with the level of comorbidities could explain the independent contribution of the amount of prescribed drugs to frailty prediction. On the other hand, findings in regard to medication type provide further evidence of the association of frailty with cardiovascular risk. In the present study, a significant part of frailty was predicted, and the different contributions of each determinant to frailty domains highlight the relevance of the integral model of frailty. The added value of a simple assessment of medication was considerable, and it should be taken into account for effective identification of frailty.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 8
Documents
We could not find any documents associated to the publication.
Related Publications

Of the same authors

Portuguese version of the Tilburg Frailty Indicator: Transcultural adaptation and psychometric validation (2015)
Article in International Scientific Journal
Coelho, T; Santos, R; Constança Paúl; Gobbens, RJJ; Lia Fernandes
Multidimensional Frailty and Pain in Community Dwelling Elderly (2017)
Article in International Scientific Journal
Coelho, T; Constança Paúl; Gobbens, RJJ; Lia Fernandes
Frailty as a predictor of short-term adverse outcomes (2015)
Article in International Scientific Journal
Coelho, T; Constança Paúl; Gobbens, RJJ; Lia Fernandes

Of the same journal

Editorial: Mood and Cognition in Old Age (2018)
Another Publication in an International Scientific Journal
Lia Fernandes; Wang, HL
Editorial: Aging and Mental Health (2017)
Another Publication in an International Scientific Journal
Lia Fernandes; Constança Paúl
Working Memory Training Coupled With Transcranial Direct Current Stimulation in Older Adults: A Randomized Controlled Experiment (2022)
Article in International Scientific Journal
Teixeira-Santos, AC; moreira, cs; Pereira, DR; Pinal, D; Fregni, F; Leite, J; Carvalho, S; Sampaio, A
The importance of neighborhood ecological assets in community dwelling old people aging outcomes: A study in Northern Portugal (2015)
Article in International Scientific Journal
Bastos, AM; Patricia Dias Pereira; Moreira, E; Morais, D; Melo de Carvalho, JM; Constança Paúl
Subjective memory complaints and decision making in young and older adults: an event-related potential study (2021)
Article in International Scientific Journal
Ruth Garrido-Chaves; Vanesa Perez; Mario Perez-Alarcón; Isabel Crespo-Sanmiguel; Tiago O. Paiva; Vanesa Hidalgo; Matias M. Pulopulos; Alicia Salvador

See all (14)

Recommend this page Top
Copyright 1996-2025 © Faculdade de Medicina Dentária da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z
Page created on: 2025-07-09 at 05:17:47 | Privacy Policy | Personal Data Protection Policy | Whistleblowing | Electronic Yellow Book