Metabolic and biological prospecting of Coreopsis tinctoria

• Type: Article in International Scientific Journal
• Date: 2012

Authors

Luis Gaspar (Author) Other; Andreia P Oliveira (Author) Other; Luis R Silva (Author) Other; Paula B Andrade (Author) FFUP; de Pinho, PG (Author) FFUP; Joao Botelho (Author) Other; Patricia Valentao (Author) FFUP

Journal

Title: Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Vol. 22

Pages: 350-358

ISSN: 0102-695X

Indexing

ISI Web of Knowledge - 10 Citations

Scopus - 10 Citations

Scientific classification

FOS: Medical and Health sciences > Basic medicine

Other information

Authenticus ID: P-002-CXV

DOI: 10.1590/s0102-695x2011005000224

Abstract (EN): Coreopsis tinctoria Nutt., Asteraceae, fl owering tops infusion has been traditionally used in many countries to control hyperglycaemia. In this work we report for the fi rst time fatty acids and volatile compounds in this species. Fifteen fatty acids and sixteen volatile compounds were determined by GC-ITMS, being saturated fatty acids and monoterpenes the main compounds. The antioxidant and antibacterial potential of this matrix was checked for the fi rst time by several in vitro assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Antibacterial capacity was assessed against Gram-positive and Gram-negative bacteria, being more effective against the fi rst. Additionally, acetylcholinesterase and butyrylcholinesterase inhibitory activity was also evaluated, but no effect was found. Our results provide evidence of a wide diversity of compounds with several biological properties, improving the knowledge on this poorly studied matrix, which can lead to an increment of the use of C. tinctoria fl owering tops, namely in food and pharmaceutical applications.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9