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Development and application of a novel peptide nucleic acid probe for the specific detection of Helicobacter pylori in gastric biopsy specimens

Title
Development and application of a novel peptide nucleic acid probe for the specific detection of Helicobacter pylori in gastric biopsy specimens
Type
Article in International Scientific Journal
Year
2007
Authors
Guimaraes, N
(Author)
Other
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Azevedo, NF
(Author)
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Figueiredo, C
(Author)
FMUP
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Keevil, CW
(Author)
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Vieira, MJ
(Author)
Other
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Journal
Vol. 45
Pages: 3089-3094
ISSN: 0095-1137
Scientific classification
FOS: Natural sciences > Biological sciences
Other information
Authenticus ID: P-004-7WG
Abstract (EN): In this work, a fluorescence in situ hybridization (FISH) method for the rapid detection of Helicobacter pylori using a novel peptide nucleic acid (PNA) probe is reported. Laboratory testing with several different bacterial species, including other Helicobacter spp., has shown that this probe is highly specific for H. pylori strains. In addition, the PNA FISH method has been successfully adapted for detection of the pathogen in paraffin embedded gastric biopsy specimens.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 6
Documents
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Guimaraes_2007 469.44 KB
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