Study of paraffin-embedded colon cancer tissue using terahertz spectroscopy

• Type: Article in International Scientific Journal
• Date: 2015

Authors

Faustino Wahaia (Author) Other; Irmantas Kasalynas (Author) Other; Dalius Seliuta (Author) Other; Gediminas Molis (Author) Other; Andrzej Urbanowicz (Author) Other; Catia D C Carvalho Silva (Author) Other; Fatima Carneiro (Author) Other; Gintaras Valusis (Author) Other; Pedro L Granja (Author) FEUP

Journal

Title: Journal of Molecular Structure

Vol. 1079

Pages: 448-453

ISSN: 0022-2860

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 23 Citations

Scopus - 27 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-009-YCA

DOI: 10.1016/j.molstruc.2014.09.024

Abstract (EN): In this work, samples of non-neoplastic and adenocarcinoma-affected human colon tissue samples were analyzed using multipoint transmission time-domain THz spectroscopy (THz-TDS) to sort out the contrast-contributing factors other than water, the main contrast mechanism factor in in-vivo or in freshly excised bio-tissue. Solving the electromagnetic inverse problem through THz-TDS and, analyzing the transmittance spectra that yielded the frequency-dependent absorption coefficient cc and refractive index n of non-neoplastic and neoplastic tissues, we show that it is possible to distinguish between non-neoplastic and neoplastic regions in paraffin-embedded dehydrated. Results and discussion are presented.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6